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Sent on Mormon-News: 13Jun01

By Vickie Speek

Myriad Genetics Discovers High Cholesterol Gene

SALT LAKE CITY, UTAH -- Myriad Genetics, Inc. has announced the discovery of a previously unknown genetic material that may be responsible for high cholesterol levels in humans. The company is listed on the Mormon Stock Index because Christopher L. Wight, its vice president and general counsel, is LDS.

Research shows that individuals from families whose members had heart attacks at an early age produce abnormal levels of the CHD2 (Coronary Heart Disease 2) gene. New data also suggests that abnormal levels of this protein are critical to the development of early-onset heart disease.

Myriad conducted the study in collaboration with scientists from the Cardiovascular Genetics Research Clinic at the University of Utah.

Scientists believe the CHD2 gene may be treatable with a new class of medication designed to lower cholesterol and reduce the risk of heart disease in those individuals with high cholesterol. Current therapies are often inadequate in lowering total cholesterol levels in many patients.

Estimates show that half of all men and one third of all women in the U.S. will develop heart disease, the most common cause of death, during their lifetime. The cost of treating heart disease in the U.S. is estimated to be over $325 billion per year.


Myriad Genetics Discovers High Cholesterol Gene
PRNewswire 5Jun01 B4
CHD2 Enzyme is in Novel Pathway, May Lead to New Class Of Cholesterol Lowering Drugs


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